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Store at room temperatureProtect from lightStore in a dry placeDo not store in a bathroomKeep all drugs in a safe placeKeep all drugs out of the reach of children and petsThrow away unused or expired drugsDo not flush down a toilet or pour down a drain unless you are told to do soCheck with your pharmacist if you have questions about the best way to throw out drugsThere may be drug take-back programs in your area.

In womenlong-term levothyroxine sodium therapy has been associated with increased bone resorptionthereby decreasing bone mineral densityespecially in post-menopausal women on greater than replacement doses or in women who are receiving suppressive doses of levothyroxine sodiumThe increased bone resorption may be associated with increased serum levels and urinary excretion of calcium and phosphorouselevations in bone alkaline phosphatase and suppressed serum parathyroid hormone levelsThereforeit is recommended that patients receiving levothyroxine sodium be given the minimum dose necessary to achieve the desired clinical and biochemical response.

Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone productsThese include urticariapruritusskin rashflushingangioedemavarious GI symptomsabdominal painnauseavomiting and diarrheafeverarthralgiaserum sickness and wheezingHypersensitivity to levothyroxine itself is not known to occur.

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