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It may take 1 to 4 weeks for desyrel to work.

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As with all antidepressantsthe use of Desyrel should be based on the consideration of the physician that the expected benefits of therapy outweigh potential risk factors.

Because the frequency of adverse drug effects is affected by diverse factorsegdrug dosemethod of detectionphysician judgmentdisease under treatmentetca single meaningful estimate of adverse event incidence is difficult to obtainThis problem is illustrated by the variation in adverse event incidence observed and reported from the inpatients and outpatients treated with DesyrelIt is impossible to determine precisely what accounts for the differences observed.

Older adults may be more sensitive to the side effects of this drugespecially drowsinessdizzinessand QT prolongationsee above

Frequency not reportedBradycardiacardiac arrhythmiaschest painECG abnormalitiesincreased risk of bleedingorthostatic hypotensionpalpitationspremature ventricular beatsQT prolongationsinus bradycardiatachycardiaTorsade de pointesventricular coupletsventricular tachycardia.

The possibility of suicide in seriously depressed patients is inherent in the illness and may persist until significant remission occursThereforeprescriptions should be written for the smallest number of tablets consistent with good patient management.

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