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Exacerbation of hepatitis B in HBV/HIV coinfected patients may occur on discontinuation.

Epivir-HBV is not approved for the treatment of HIV-1 infection because the lamivudine dosage in Epivir-HBV is subtherapeutic and monotherapy is inappropriate for the treatment of HIV-1 infectionHIV-1 resistance may emerge in chronic hepatitis B-infected patients with unrecognized or untreated HIV-1 infectionHIV counseling and testing should be offered to all patients before beginning treatment with EPIVIRHBV and periodically during treatmentsee Warnings and Precautions5.3

If you are pregnantyour name may be listed on a pregnancy registryThis is to track the outcome of the pregnancy and to evaluate any effects of lamivudine on the baby.

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