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There are some studies on the use of florinef an aldosterone-like drug in cases of chronic fatigue syndrome and the results have been a wash between positive and negative.

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Corticosteroids are thought to actat least in partby controlling the rate of synthesis of proteinsAlthough there are a number of instances in which the synthesis of specific proteins is known to be induced by corticosteroidsthe links between the initial actions of the hormones and the final metabolic effects have not been completely elucidated.

When administered concurrentlythe following drugs may interact with adrenal corticosteroids.

Other adverse reactions that may occur following the administration of a corticosteroid are necrotizing angiitisthrombophlebitisaggravation or masking of infectionsinsomniasyncopal episodesand anaphylactoid reactions.

Adequate studies have not been performed in animals to determine whether fludrocortisone acetate has carcinogenic or mutagenic activity or whether it affects fertility in males or females.

The use of Florinef AcetateFludrocortisone Acetate Tablets USPin patients with active tuberculosis should be restricted to those cases of fulminating or disseminated tuberculosis in which the corticosteroid is used for the management of the disease in conjunction with an appropriate antituberculous regimenIf corticosteroids are indicated in patients with latent tuberculosis or tuberculin reactivityclose observation is necessary since reactivation of estrace 2mg ivf side effects. the disease may occurDuring prolonged corticosteroid therapy these patients should receive chemoprophylaxis.

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